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Due to the current Continuing Resolution, the FY17 Defense Appropriations bill has not been passed. Although funds have not been appropriated for the Department of Defense Peer Reviewed Medical Research Program (PRMRP), the PRMRP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY17 funding opportunities.
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DoD Anticipated Funding for the Peer Reviewed Medical Research Program

April 6, 2017 08:50 AM
 
Defense Health Program
Department of Defense Peer Reviewed Medical Research Program
Anticipated Funding Opportunities for Fiscal Year 2017 (FY17)
 
Due to the current Continuing Resolution, the FY17 Defense Appropriations bill has not been passed.  Although funds have not been appropriated for the Department of Defense Peer Reviewed Medical Research Program (PRMRP), the PRMRP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY17 funding opportunities.
 
FY17 PRMRP Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on Grants.gov in May 2017.  Pre-application and application deadlines will be available when the Program Announcements are released.  This pre-announcement should not be construed as an obligation by the Government, and funding of research projects received in response to these Program Announcements is contingent on the availability of Federal funds appropriated for the PRMRP.
 
As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA) J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
 
Congressionally Directed Topic Areas.  All applications submitted to the PRMRP must address at least one of the FY17 PRMRP Congressionally directed topic areas.  As of the release date of this pre-announcement, the FY17 PRMRP Topic Areas have not been finalized.  This pre-announcement should not be construed as an obligation by the Government to include any of these Topic Areas or others in the FY17 PRMRP.  The potential FY17 PRMRP Topic Areas are:
 
Acute Lung Injury
Antimicrobial Resistance
Arthritis
Burn Pit Exposure
Chronic Migraine and Post-Traumatic Headache
Congenital Heart Disease
Constrictive Bronchiolitis
Diabetes
Diarrheal Diseases
Dystonia
Early Trauma Thermal Regulation
Eating Disorders
Emerging Infectious Diseases
Epidermolysis Bullosa
Focal Segmental Glomerulosclerosis
Fragile X Syndrome
Guillain-Barré Syndrome
Hepatitis B and C Hereditary Angioedema
Hydrocephalus
Immunomonitoring of Intestinal Implants
Inflammatory Bowel Diseases
Influenza
Integrative Medicine
Interstitial Cystitis
Malaria
Metals Toxicology
Mitochondrial Disease
Musculoskeletal Disorders
Nanomaterials for Bone Regeneration
Non-Opioid Pain Management
Pancreatitis
Pathogen-Inactivated Dried Cryoprecipitate
Polycystic Kidney Disease
Post-Traumatic Osteoarthritis
Pulmonary Fibrosis Respiratory Health
Rett Syndrome
Rheumatoid Arthritis
Scleroderma
Sleep Disorders
Spinal Muscular Atrophy
Sustained-Release Drug Delivery
Tinnitus
Tuberculosis
Vaccine Development for Infectious Disease
Vascular Malformations
Women’s Heart Disease
 
Military Relevance:  Relevance to the healthcare needs of the military Service members, Veterans, and beneficiaries is a key feature of each FY17 PRMRP award mechanism.
 
Clinical Trial Award
Assistant Professor level or above (or equivalent)
Preproposal submission is required; application submission is by invitation only.
Supports the rapid implementation of clinical trials of novel interventions with the potential to have a significant impact on patient care in the topic area(s) of interest.
Proposed projects may range from small proof-of-concept trials through large-scale, definitive trials.
Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration by the PRMRP Grants.gov application submission deadline.
Funding limit not defined; requested funding must be appropriate for the scope of work proposed
Maximum period of performance is 4 years
 
Discovery Award
All Investigators
Supports the exploration of a highly innovative new concept or untested theory.
Not intended to support the logical progression of an already established line of questioning.
Clinical trials will not be funded.
Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborators, and their organization(s).
Maximum of $200,000 for direct costs (plus indirect costs)
Maximum period of performance is 18 months
 
Focused Program Award
Full Professor level or above (or equivalent)
Preproposal submission is required; application submission is by invitation only.
Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects addressing an overarching goal.
Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory findings to clinical applications.
Projects may range from exploratory/ hypothesis-developing through small-scale clinical trials that together will address the overarching goal/question.
Research team of highly qualified, multidisciplinary project leaders should be led by a PI with demonstrated success in directing large, focused projects.
Maximum of $10 million for total costs (includes direct and indirect costs)
Maximum period of performance is 4 years
 
 
Investigator-Initiated Research Award
Assistant Professor level or above (or equivalent)
Preproposal submission is required; application submission is by invitation only.
Supports research that will make an original and important contribution to the field of research or patient care in the topic area(s) of interest.
Partnering PI Option available.
Clinical trials will not be funded.
Maximum of $1.2 million for direct costs (plus indirect costs)
Maximum of $1.5 million for direct costs (plus indirect costs) for applications including a Partnering PI Option
Maximum period of performance is 3 years
 
 
Technology/ Therapeutic Development Award
Assistant Professor level or above (or equivalent)
Supports the translation of promising preclinical findings into clinical applications for prevention, detection, diagnosis, treatment, or quality of  life.
Product-oriented (e.g., device, drug, clinical guidelines). The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product.
Clinical trials will not be funded.
Preproposal submission is required; application submission is by invitation only.
Maximum of $3.0 million for direct costs (plus indirect costs)
Maximum period of performance is 3 years
 
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline.  All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov.  A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
 
Applications must be submitted through the federal government’s single-entry portal, Grants.gov. Submission deadlines are not available until the Program Announcements are released.  For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).
 
Point of Contact:
CDMRP Public Affairs 301-619-9783
usarmy.detrick.medcom-cdmrp.mbx.cdmrp-public-affairs@mail.mil
 
 

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